Endocrine Abstracts

Metabolic alterations have long been known to occur in the transition to prostate cancer, from alterations in central metabolism to lipid metabolism and local steroid biosynthesis. However the upstream events that lead to these alterations have not been comprehensively assessed. In this presentation I will draw together genomic, epigenomic and transcriptomic analysis, together with metabolic profiling. Overlaying the effects of androgen signaling on these pathways and metaboli...